royal皇家88(中国)

    royal皇家88(中国) /药靶模型 /GPCR靶点细胞 /Class A(Rhodopsin) /CCR10/CHO

    CCR10/CHO

    CBP71355

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    I. Background
    CCR10 is a chemokine receptor. Its ligands are CCL27 and CCL28. This receptor is normally expressed by melanocytes, plasma cells and skin-homing T cells.
     
    II. Introduction
    Host Cell:

    CHO

    Stability: 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
    Freeze Medium: 90% FBS+10% DMSO
    Culture Medium: F12K+10%FBS+5μg/ml Puromycin
    Mycoplasma Status: Negative
    Storage: Liquid nitrogen immediately upon delivery
    Application(s):

    Functional assay for CCR10

    Transducer: Gi
     
    Ⅲ. Description of Host Cell Line
    Organism: Hamster
    Tissue: Ovary
    Morphology: Epithelial
    Growth Properties: Adherent
     
    Ⅳ. Representative Data

    Figure 1. Recombinant CCR10/CHO constitutively expressing CCR10.

    Figure 2. CCL27 effect on CCR10/CHO-K1 clone 5.


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